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Body weight and Cannabis/Endocannabinoids: how are they interconnected?

Endocannabinoids and obesity

Research at the Charité Hospital in Berlin showed that the concentrations of circulating endocannabinoids (anandamide and 2-AG) were significantly elevated in obese compared to lean women. On the other hand, expression of the CB1 receptor and of the enzyme fatty acid amide hydrolase (FAAH), which is mainly responsible for the degradation of anandamide, were significantly increased in fat tissue of obese subjects compared to controls. Researchers note that their "findings support the presence of a peripheral endocannabinoid system that is upregulated in human obesity (BMI >26)."

Sources: www.cannabis-med.org; Engeli S, et al. Diabetes 2005;54(10):2838-43.

Body mass index and cannabis

US researchers investigated the correlation between cannabis use and body mass index (BMI). The BMI is a measure for the relationship between weight and height. A high BMI is found in obese subjects. The study with 297 women showed that despite cannabis is known to increase appetite, cannabis use in the past year was more common in subjects with low BMI, that is slim women.

Sources:[www.cannabis-med.org]; Warren M, et al. J Addict Dis 2005;24(3):95- 100.)

Calculate your Body Mass Index

  • Bekanntlich regt Cannabis den Appetit an. Trotzdem bleiben Cannabiskonsumentinnen schlank, wie jetzt bei einer Studie in Deutschland herausgefunden wurde. Haben Frauen jedoch viele körpereigene Cannabinoide im Blut, neigen sie zu Übergewicht.
  • Obésité : D'un còté il y a surrégulation du système des cannabinoïdes endogènes dans l'obésité, de l'autre des femmes ayant consommé du cannabis au cours des dernières années sont sveltes, bien que le cannabis ait un effet stimulant l'appétit. Décidément, les cannainoïdes internes et externes jouent un rôle important dans la régulation du poids corporel.
Update Friday 18 November 2005 12:26, published Friday 21 October 2005 01:04