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Cannabinoid receptors and nutrition

A receptor antagonist reduces food intake in animals

In animal experiments with rats the effects of the CB1 receptor antagonist AM 251 on feeding behaviour were investigated. The drug dose-dependently decreased food intake and induced nausea.

Researchers conclude that the antagonist "may reduce food intake in part by inducing nausea or malaise."

see also: Rimonabant/Acomplia


(McLaughlin PJ, et al. Psychopharmacology (Berl) 2005;180(2):286-93.)

  • Récepteurs aux cannabinoïdes. Prise alimentaire. Antagonistes du récepteur CB1 AM 251
published Saturday 16 July 2005 03:25